Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 5/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420260 | 1.00 | NPY5R (0.47) | NPY5RKDM1AHSD11B1MALT1PTGS2 | |
| SCHEMBL8423929 | 0.94 | NPY5R (0.51) | NPY5RHSD11B1PTGS2PTGS1 | |
| SCHEMBL8421776 | 0.91 | KDM1A (0.47) | KDM1AMALT1PTGS2AURKAPTGS1 | |
| SCHEMBL8420766 | 0.91 | KDM1A (0.46) | NPY5RKDM1ACNR1 | |
| SCHEMBL8421075 | 0.91 | KDM1A (0.48) | NPY5RKDM1AHSD11B1CNR1AURKA | |
| SCHEMBL8641119 | 0.90 | AURKA (0.46) | KDM1AMALT1PTGS2AURKAPTGS1 | |
| SCHEMBL8420731 | 0.88 | KDM1A (0.43) | KDM1AMALT1PTGS2AURKA | |
| SCHEMBL8420906 | 0.88 | KDM1A (0.46) | KDM1AMALT1PTGS2AURKA | |
| SCHEMBL8422266 | 0.88 | KDM1A (0.43) | KDM1AMALT1PTGS2AURKA | |
| SCHEMBL8422366 | 0.88 | KDM1A (0.46) | KDM1AMALT1PTGS2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |