Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420260 | 0.94 | NPY5R (0.47) | NPY5RHSD11B1PTGS2PTGS1 | |
| SCHEMBL8424151 | 0.94 | NPY5R (0.47) | NPY5RHSD11B1PTGS2PTGS1 | |
| SCHEMBL8641577 | 0.89 | PTGS2 (0.49) | NPY5RHSD11B1PTGS2ACLYPTGES2 | |
| SCHEMBL8422371 | 0.87 | MAPT (0.45) | NPY5RHSD11B1CYP2C9MEN1KMT2A | |
| SCHEMBL8422144 | 0.86 | MAPT (0.45) | NPY5RPTGS2CYP2C9MEN1KMT2A | |
| SCHEMBL8421075 | 0.85 | KDM1A (0.48) | NPY5RHSD11B1ACLYPTGES2MEN1 | |
| SCHEMBL8420766 | 0.85 | KDM1A (0.46) | NPY5RACLYPTGES2MEN1KMT2A | |
| SCHEMBL8639178 | 0.85 | PTGS2 (0.43) | NPY5RHSD11B1PTGS2ACLYPTGES2 | |
| SCHEMBL8421857 | 0.84 | UQCRB (0.43) | NPY5RPTGS2CYP2C9MEN1KMT2A | |
| SCHEMBL8421776 | 0.84 | KDM1A (0.47) | PTGS2MEN1KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |