Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816406 | 0.84 | MEN1 (0.47) | HTTSMN1; SMN2CES2CES1MEN1 | |
| SCHEMBL2097486 | 0.84 | GSK3B (0.53) | GSK3BSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL21852336 | 0.84 | MEN1 (0.47) | HTTSMN1; SMN2CES2CES1MEN1 | |
| SCHEMBL9908793 | 0.84 | GSK3B (0.48) | GSK3BHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22641091 | 0.84 | GSK3B (0.53) | GSK3BSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL13622409 | 0.83 | LMNA (0.56) | HTTSMN1; SMN2CES2CES1MEN1 | |
| SCHEMBL6182736 | 0.82 | HDAC1 (0.56) | GSK3BHTTMEN1KMT2AMAPT | |
| SCHEMBL18356295 | 0.82 | GSK3B (0.47) | GSK3BSMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL5660140 | 0.81 | LMNA (0.48) | HTTSMN1; SMN2CES2CES1MEN1 | |
| SCHEMBL3899593 | 0.81 | HTT (0.52) | HTTSMN1; SMN2CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103449946-B | Preparation method of alpha-monochlorinated ketone compound | UNIV HUANGSHAN | 2015-01-14 | — | — | CN | disclosed |
| CN-103449946-A | Preparation method of alpha-monochlorinated ketone compound | UNIV HUANGSHAN | 2013-12-18 | — | — | CN | disclosed |
| CN-102875349-A | Production method of o-azodibenzoic acid intermediate | WANG DONG | 2013-01-16 | — | — | CN | disclosed |
| CN-102838467-A | Synthetic process of phthalic acid intermediate | WU MENGYUN | 2012-12-26 | — | — | CN | disclosed |
| EP-0493617-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE (-)-2-HALO-1-(SUBSTITUTED PHENYL)ETHANOL | KANEGAFUCHI CHEMICAL IND (JP) | 1999-10-06 | — | — | EP | disclosed |