Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421173 | 1.00 | ALDH1A1 (0.54) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL5981245 | 0.87 | ALDH1A1 (0.46) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL4602778 | 0.87 | ALDH1A1 (0.67) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL8425121 | 0.87 | ALDH1A1 (0.67) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL25788052 | 0.87 | ALDH1A1 (0.67) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL3716464 | 0.87 | ALDH1A1 (0.67) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL23888964 | 0.84 | KMT2A (0.61) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL3830542 | 0.84 | ALDH1A1 (0.55) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL28459313 | 0.82 | ALDH1A1 (0.60) | ALDH1A1PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL19924675 | 0.82 | IRAK4 (0.47) | ALDH1A1KMT2AMEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866036-A | HIGH POLARIZATION; HIGH SPEED SWITCHES; HIGH BIREFRINGENCE | DISPLAYTECH, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5061814-A | High tilt ferroelectric liquid crystal compounds and compositions | DISPLAYTECH, INC. (US) | 1991-10-29 | — | — | US | disclosed |