Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 10/20 | 0.49 |
| ▸ | IKBKB | O14920 | 7/20 | 0.49 |
| ▸ | RARB | P10826 | 6/20 | 0.46 |
| ▸ | RARG | P13631 | 6/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | GOT1 | P17174 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888166 | 0.89 | RARA (0.55) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL8424858 | 0.85 | RARA (0.52) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL8426205 | 0.84 | RARA (0.51) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL8428653 | 0.83 | RARA (0.50) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL5888296 | 0.83 | RARA (0.48) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL8694753 | 0.83 | RARA (0.48) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL8617706 | 0.83 | RARA (0.51) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL5887970 | 0.83 | RARA (0.60) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL5887963 | 0.83 | RARA (0.60) | RARAIKBKBRARBRARGPGR | |
| SCHEMBL5887932 | 0.82 | RARA (0.71) | RARAIKBKBRARBRARGPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776885-B1 | Diaromatic compounds with an adamantyl group in the ortho position, pharmaceutical and cosmetic compositions containing them and uses | CIRD GALDERMA (FR) | 1999-10-27 | — | — | EP | disclosed |
| EP-0776885-A1 | Diaromatic compounds with an adamantyl group in the ortho position, pharmaceutical and cosmetic compositions containing them and uses | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-06-04 | — | — | EP | disclosed |