⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425985 | 0.73 | RIPK1 (0.30) | — | |
| SCHEMBL9628883 | 0.64 | — | — | |
| SCHEMBL11708859 | 0.64 | — | — | |
| SCHEMBL11708865 | 0.64 | — | — | |
| SCHEMBL4842476 | 0.63 | — | — | |
| SCHEMBL7383796 | 0.60 | — | — | |
| SCHEMBL9732000 | 0.58 | — | — | |
| SCHEMBL9731985 | 0.58 | — | — | |
| SCHEMBL12809306 | 0.58 | — | — | |
| SCHEMBL5995075 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |