Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425761 | 0.88 | TDP1 (0.41) | NR1I2PPARGESR1PGRTDP1 | |
| Iodide SCHEMBL9760681 | 0.87 | TDP1 (0.37) | NR1I2PPARGESR1PGRTDP1 | |
| SCHEMBL8425864 | 0.85 | TDP1 (0.39) | NR1I2PPARGESR1PGRTDP1 | |
| Iodide SCHEMBL9004570 | 0.82 | NR1I2 (0.41) | NR1I2PPARGESR1PGRTDP1 | |
| SCHEMBL9667500 | 0.82 | TDP1 (0.42) | NR1I2PPARGESR1PGRTDP1 | |
| SCHEMBL9667504 | 0.82 | TDP1 (0.42) | NR1I2PPARGESR1PGRTDP1 | |
| SCHEMBL9667985 | 0.82 | TDP1 (0.42) | NR1I2PPARGESR1PGRTDP1 | |
| SCHEMBL9667991 | 0.82 | TDP1 (0.42) | NR1I2PPARGESR1PGRTDP1 | |
| SCHEMBL9662765 | 0.82 | MAPT (0.48) | NR1I2PPARGESR1PGRTDP1 | |
| SCHEMBL9662774 | 0.82 | MAPT (0.48) | NR1I2PPARGESR1PGRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969131-A | OR PRECURSORS; CHEMICAL INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0634415-A2 | Cephem compound, its production and its use for producing cephem antibiotics | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |