Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.61 |
| ▸ | ARG2 | P78540 | 4/20 | 0.55 |
| ▸ | ARG1 | P05089 | 3/20 | 0.55 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.55 |
| ▸ | NOS2 | P35228 | 6/20 | 0.52 |
| ▸ | NOS1 | P29475 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23214374 | 1.00 | GSR (0.61) | GSRARG2ARG1DDAH1NOS2 | |
| SCHEMBL8425214 | 1.00 | GSR (0.61) | GSRARG2ARG1DDAH1NOS2 | |
| SCHEMBL5287112 | 0.98 | GSR (0.64) | GSRARG2ARG1DDAH1NOS2 | |
| Hydrochloric Acid SCHEMBL11434603 | 0.95 | GSR (0.61) | GSRARG2ARG1DDAH1NOS2 | |
| SCHEMBL29268469 | 0.91 | — | — | |
| SCHEMBL28670456 | 0.89 | DDAH1 (0.50) | GSRARG2ARG1DDAH1NOS2 | |
| SCHEMBL6741106 | 0.88 | GSR (0.76) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL4848672 | 0.88 | GSR (0.76) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL8894128 | 0.88 | GSR (0.76) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL9829771 | 0.88 | GSR (0.76) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994502-A | CONTACTING A PEPTIDE CONTAINING ASPARAGINE IN A GLYCOSYLATION RECOGNITION MOTIF WITH A COMPOUND OF GLUCOSE-MANNOSE-N-ACETYLGLUCOSAMINE-PYROPHOSPHATE-DOLICHOL AND THE ENZYME, ISOLATING FORMED GLYCOPEPTIDE | NATIONAL INSTITUTES OF HEALTH | 1999-11-30 | — | — | US | disclosed |
| US-5721338-A | BIOSYNTHESIS OF GLYCOPEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-02-24 | — | — | US | disclosed |