Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 16/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425246 | 1.00 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2AAMY1AMAPT | |
| SCHEMBL6951495 | 0.95 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2AAMY1AMAPT | |
| SCHEMBL6951498 | 0.95 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2AAMY1AMAPT | |
| SCHEMBL8425443 | 0.87 | KAT8 (0.55) | L3MBTL1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL8425442 | 0.87 | KAT8 (0.55) | L3MBTL1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL8425597 | 0.86 | KAT8 (0.40) | L3MBTL1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8425593 | 0.86 | KAT8 (0.40) | L3MBTL1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8427580 | 0.85 | KDM4E (0.38) | L3MBTL1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8427562 | 0.85 | KAT8 (0.41) | L3MBTL1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8427578 | 0.85 | KDM4E (0.38) | L3MBTL1MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |