Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.54 |
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | PROC | P04070 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 8/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423785 | 0.92 | F10 (0.59) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8425641 | 0.91 | F10 (0.58) | F10PLGPROCF2PRSS1 | |
| SCHEMBL2330450 | 0.86 | F10 (0.69) | F10PLGPROCF2PRSS1 | |
| SCHEMBL7424685 | 0.86 | FNTA (0.49) | F10 | |
| SCHEMBL8425655 | 0.85 | F10 (0.46) | F10PLGPROCF2 | |
| SCHEMBL8425668 | 0.83 | FNTA (0.41) | F10PLGPROCF2 | |
| SCHEMBL2328900 | 0.81 | F10 (0.70) | F10PLGPROCF2PRSS1 | |
| SCHEMBL8427867 | 0.80 | FNTA (0.44) | F10PLGPROCF2PRSS1 | |
| SCHEMBL2328991 | 0.80 | F10 (0.71) | F10PLGPROCF2PRSS1 | |
| SCHEMBL2326662 | 0.79 | F10 (0.72) | F10PLGPROCF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |