Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PROC | P04070 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 3/20 | 0.40 |
| ▸ | FNTB | P49356 | 3/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331634 | 0.87 | F10 (0.56) | F10F2PLGPROC | |
| SCHEMBL8425359 | 0.85 | F10 (0.54) | F10F2PLGPROC | |
| SCHEMBL7424685 | 0.82 | FNTA (0.49) | F10DRD4DRD3DRD2FNTA | |
| SCHEMBL8423957 | 0.82 | DRD4 (0.42) | F10DRD4DRD3DRD2PLG | |
| SCHEMBL8425641 | 0.81 | F10 (0.58) | F10F2PLGPROC | |
| SCHEMBL2328117 | 0.81 | F10 (0.46) | F10DRD4DRD3DRD2F2 | |
| SCHEMBL8425668 | 0.80 | FNTA (0.41) | F10DRD3DRD2F2PLG | |
| SCHEMBL8423785 | 0.80 | F10 (0.59) | F10F2PLGPROC | |
| SCHEMBL2325190 | 0.78 | F10 (0.68) | F10F2PLGPROC | |
| SCHEMBL8427867 | 0.77 | FNTA (0.44) | F10F2PLGPROCFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |