Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 14/20 | 0.39 |
| ▸ | STK3 | Q13188 | 6/20 | 0.39 |
| ▸ | STK26 | Q9P289 | 3/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146816 | 0.90 | ADK (0.46) | — | |
| SCHEMBL8425528 | 0.84 | ADK (0.43) | LRRK2STK3STK26PRKACAPRKACG | |
| SCHEMBL8161842 | 0.75 | — | — | |
| SCHEMBL2039600 | 0.73 | ADK (0.52) | — | |
| SCHEMBL8147200 | 0.73 | ADK (0.58) | — | |
| SCHEMBL8146817 | 0.73 | ADK (0.53) | — | |
| SCHEMBL2034210 | 0.72 | ADK (0.48) | — | |
| SCHEMBL2037126 | 0.72 | ADK (0.47) | — | |
| SCHEMBL2035528 | 0.72 | ADK (0.56) | — | |
| SCHEMBL8267956 | 0.72 | HPGD (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |