Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425854 | 0.94 | NOTUM (0.41) | NOTUMPOLBACACBMEN1KMT2A | |
| SCHEMBL8423325 | 0.92 | NOTUM (0.39) | NOTUMPOLBACACBMEN1KMT2A | |
| SCHEMBL9229924 | 0.90 | NOTUM (0.40) | NOTUMPOLBACACBMEN1KMT2A | |
| SCHEMBL8425467 | 0.87 | NOTUM (0.41) | NOTUMPOLBACACBMEN1KMT2A | |
| SCHEMBL8424243 | 0.87 | NOTUM (0.41) | NOTUMPOLBACACBMEN1KMT2A | |
| SCHEMBL8424561 | 0.84 | NOTUM (0.39) | NOTUMPOLBACACBMEN1KMT2A | |
| SCHEMBL9065090 | 0.81 | ALDH1A1 (0.44) | NOTUMSMN1; SMN2CNR2ALDH1A1LMNA | |
| SCHEMBL8425728 | 0.80 | NOTUM (0.41) | NOTUMPOLBACACBMEN1KMT2A | |
| SCHEMBL8424321 | 0.80 | NOTUM (0.41) | NOTUMPOLBACACBMEN1KMT2A | |
| SCHEMBL8428186 | 0.80 | NOTUM (0.40) | NOTUMPOLBACACBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636616-B1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5484933-A | Process for production of fluoroalkane carboxamide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0636616-A1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |