⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1370210 | 0.70 | — | — | |
| SCHEMBL352063 | 0.67 | — | — | |
| SCHEMBL1074378 | 0.65 | — | — | |
| SCHEMBL15994694 | 0.60 | — | — | |
| Propane SCHEMBL28168524 | 0.57 | — | — | |
| Propane SCHEMBL4449197 | 0.57 | — | — | |
| SCHEMBL2723129 | 0.56 | — | — | |
| SCHEMBL98977 | 0.56 | — | — | |
| SCHEMBL1151227 | 0.53 | — | — | |
| SCHEMBL2336751 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955464-A | USE OF THE RECEPTOR TYROSINE KINASE INHIBITORY PROPERTIES OF THE COMPOUNDS IN THE TREATMENT OF PROLIFERATIVE DISEASE SUCH AS CANCER | ZENECA LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |