Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425629 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL195525 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL6398790 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL6398117 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL10817448 | 0.82 | TDP1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL10813302 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL5723978 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL4476414 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL5723982 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL6774275 | 0.78 | KDM4E (0.41) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856556-A | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0102239-B1 | AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS INTERMEDIATES IN THE PREPARATION OF CARBAPENEM ANTIBIOTICS | SANKYO COMPANY LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |
| EP-0102239-A1 | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY LIMITED (JP) | 1984-03-07 | — | — | EP | disclosed |