SCHEMBL8425733

SCHEMBL8425733

CC(c1ccccc1)c1cc(Cc2ccccc2)c(O)c(C(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.62
PTPN2 P17706 3/20 0.62
PTPN6 P29350 3/20 0.62
LDHA P00338 2/20 0.44
LDHB P07195 2/20 0.44
HMGB1 P09429 1/20 0.43
CXCL12 P48061 1/20 0.43
HNF4A P41235 1/20 0.43
BCL2 P10415 1/20 0.43
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9652059 0.89 PTPN1 (0.66) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL10869295 0.87 BCL2 (0.48) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL9652075 0.85 PTPN1 (0.61) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL10907289 0.83 BCL2 (0.52) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL9251745 0.83 PTPN1 (0.62) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL10583340 0.83 PTPN1 (0.49) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL9509289 0.83 PTPN1 (0.52) PTPN1PTPN2PTPN6LDHALDHB
SCHEMBL10906011 0.80 ESR1 (0.50) PTPN1PTPN2PTPN6BCL2
SCHEMBL11755681 0.79 THRB (0.46) PTPN1HMGB1HNF4AALDH1A1HPGD
SCHEMBL9509619 0.79 PTPN1 (0.50) PTPN1PTPN2PTPN6LDHALDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547629-B2 Color developers and sheets thereof SANYO CHEMICAL IND LTD (JP) 1999-10-27 EP disclosed
US-5382560-A Metal salt of styrene-salicyclic acid compound SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-01-17 US disclosed
US-5141557-A Mixture of benzoic acid salt, anionic surfactant, and novolak phenolic resin BROTHER KOGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed