⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195897 | 0.80 | — | — | |
| SCHEMBL8708385 | 0.78 | — | — | |
| SCHEMBL11449339 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL7749089 | 0.76 | TSHR (0.56) | — | |
| SCHEMBL10855337 | 0.76 | TSHR (0.56) | — | |
| SCHEMBL11337174 | 0.76 | TSHR (0.56) | — | |
| SCHEMBL11327918 | 0.76 | TSHR (0.56) | — | |
| SCHEMBL6040454 | 0.73 | — | — | |
| SCHEMBL4701234 | 0.72 | — | — | |
| SCHEMBL20458788 | 0.71 | MGLL (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209977-B | Decitabine intermediate compound VI | 鲁南制药集团股份有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-110963953-B | Sulfaast tosilate process impurity I and preparation method and application thereof | 植恩生物技术股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-112209977-A | Decitabine intermediate compound VI | 鲁南制药集团股份有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-108440358-B | Preparation method of suplatast tosilate and intermediate | 重庆柳江医药科技有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-110981771-A | Preparation method and application of impurity E of suplatast tosilate process | 重庆植恩药业有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110963953-A | Sulfaast tosilate process impurity I and preparation method and application thereof | 重庆植恩药业有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-113754607-B | Oxadiazole compound and application thereof | 沈阳化工大学 | 2023-09-05 | — | — | CN | disclosed |
| US-11697648-B2 | Fused pyrimidine pyridinone compounds as JAK inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-07-11 | — | — | US | disclosed |
| CN-112209977-B | Decitabine intermediate compound VI | 鲁南制药集团股份有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-112552220-B | Preparation method of suplatast tosilate | 植恩生物技术股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-114901659-A | Fused pyrimidinone compounds as JAK inhibitors | 施万生物制药研发IP有限责任公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-110963953-B | Sulfaast tosilate process impurity I and preparation method and application thereof | 植恩生物技术股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-111849464-B | Polymer fluorescent probe and application thereof | 中国科学技术大学 | 2021-12-14 | — | — | CN | disclosed |
| EP-0004134-A1 | Beta-lactam antibacterial agents, their pharmaceutical compositions and process for their preparation | BEECHAM GROUP PLC (GB) | 1979-09-19 | — | — | EP | disclosed |
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4134918-A | ENZYME INHIBITORS, ANTIBODY INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1979-01-16 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4038409-A | FUNGICIDES, BACTERICIDES, PROTOZOICIDES | SYNTEX (U.S.A.) INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-4015001-A | Control of insects by nitro(tetrahydro-2H-1,3-thiazin-2-ylidene)methyl aldehydes and ketones | SHELL OIL COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-3962225-A | NITRO(TETRAHYDRO-2H-1,3-THIAZIN-2-YLIDENE)METHYL ALDEHYDES AND KETONES | SHELL OIL COMPANY (US) | 1976-06-08 | — | — | US | disclosed |