Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 14/20 | 0.47 |
| ▸ | CHKA known ✓ | P35790 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 14/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8428013 | 1.00 | HDAC8 (0.48) | HDAC8BCHEACHECHKA | |
| Bromide SCHEMBL8425884 | 0.98 | HDAC8 (0.50) | HDAC8BCHEACHECHKA | |
| SCHEMBL21350643 | 0.95 | HDAC8 (0.52) | HDAC8BCHEACHECHKA | |
| Bromide SCHEMBL5489286 | 0.90 | KMT2A (0.60) | ACHE | |
| Hydrochloric Acid SCHEMBL8775080 | 0.86 | KMT2A (0.60) | ACHE | |
| Bromide SCHEMBL8663821 | 0.85 | KMT2A (0.48) | HDAC8ACHE | |
| SCHEMBL8660074 | 0.83 | KMT2A (0.50) | HDAC8ACHE | |
| Hydrochloric Acid SCHEMBL11600265 | 0.81 | MEN1 (0.48) | HDAC8ACHE | |
| Bromide SCHEMBL10609243 | 0.80 | HDAC8 (0.52) | HDAC8BCHEACHE | |
| SCHEMBL15164193 | 0.79 | HDAC8 (0.56) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476338-B1 | Polyviologen modified electrode and use thereof | DAISO CO LTD (JP) | 1999-11-03 | — | — | EP | disclosed |
| US-5232574-A | Water and solvent insolubility | DAISO CO. LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0476338-A2 | Polyviologen modified electrode and use thereof | DAISO CO., LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |