Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18603169 | 0.87 | CHRM2 (0.40) | CHRM2CHRM1CHRM3CHRM4KMT2A | |
| SCHEMBL19934329 | 0.81 | CHRM2 (0.47) | CHRM2CHRM1CHRM3CHRM4KMT2A | |
| SCHEMBL20599589 | 0.81 | — | — | |
| SCHEMBL10494125 | 0.81 | CHRM2 (0.42) | CHRM2CHRM1CHRM3CHRM4KMT2A | |
| SCHEMBL10494118 | 0.81 | CHRM2 (0.42) | CHRM2CHRM1CHRM3CHRM4KMT2A | |
| SCHEMBL29308581 | 0.81 | CHRM2 (0.47) | CHRM2CHRM1CHRM3CHRM4KMT2A | |
| SCHEMBL9073688 | 0.80 | — | — | |
| SCHEMBL14141275 | 0.79 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CHRM4KMT2A | |
| SCHEMBL14099455 | 0.79 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CHRM4KMT2A | |
| SCHEMBL6652812 | 0.79 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CHRM4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912247-A | BLOOD FLOW INHIBITION; SIDE EFFECT REDUCTION | KANEBO, LTD. (JP) | 1999-06-15 | — | — | US | disclosed |
| EP-0743308-A2 | Quinazoline compound and anti-tumor agent containing said compound as an active ingredient | KANEBO, LTD. (JP) | 1996-11-20 | — | — | EP | disclosed |