Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29308581 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL30891555 | 0.88 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL6653691 | 0.86 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL10449210 | 0.86 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL14141163 | 0.86 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL18250835 | 0.81 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8425951 | 0.81 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL12990820 | 0.81 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL24854738 | 0.81 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL8460680 | 0.81 | CHRM2 (0.39) | CHRM2CHRM1CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4101859-A1 | 4'-OXYMETHYLPHOSPHONATE NUCLEOTIDE ANALOGS AND OLIGONUCLEOTIDES COMPRISING THE SAME | Dicerna Pharmaceuticals, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| EP-3506909-B1 | 4'-PHOSPHATE ANALOGS AND OLIGONUCLEOTIDES COMPRISING THE SAME | DICERNA PHARMACEUTICALS INC (US) | 2022-06-29 | — | — | EP | disclosed |
| US-20190177729-A1 | 4'-PHOSPHATE ANALOGS AND OLIGONUCLEOTIDES COMPRISING THE SAME | NOVO NORDISK A/S (DK) | 2019-06-13 | — | — | US | disclosed |
| WO-2018045317-A1 | 4'-PHOSPHATE ANALOGS AND OLIGONUCLEOTIDES COMPRISING THE SAME | DICERNA PHARMACEUTICALS, INC. (US) | 2018-03-08 | — | — | WO | disclosed |