SCHEMBL8426124

SCHEMBL8426124

Cc1ccc2nn(S)nc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.45
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 4/20 0.43
RAB9A P51151 4/20 0.43
MAPT P10636 4/20 0.43
NPC1 O15118 3/20 0.43
GAA P10253 2/20 0.43
HPGD P15428 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 3/20 0.40
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
NCK1 P16333 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9909829 0.79 NQO2 (0.46) NQO2ALDH1A1KDM4ERAB9AMAPT
SCHEMBL7086885 0.77 NPC1 (0.47) NQO2ALDH1A1KDM4ERAB9AMAPT
SCHEMBL28818202 0.77 NQO2 (0.45) NQO2ALDH1A1KDM4ERAB9AMAPT
SCHEMBL3221922 0.74 NPC1 (0.73) ALDH1A1KDM4ERAB9AMAPTNPC1
SCHEMBL12204560 0.74 NQO2 (0.42) NQO2ALDH1A1KDM4ERAB9AMAPT
SCHEMBL17897165 0.72 NQO2 (0.41) NQO2ALDH1A1KDM4ERAB9AMAPT
SCHEMBL3226780 0.71 KDM4E (0.63) NQO2ALDH1A1KDM4ERAB9AMAPT
SCHEMBL9704263 0.70 RAB9A (0.57) ALDH1A1KDM4ERAB9AMAPTNPC1
SCHEMBL7364726 0.70 MAPT (0.39) NQO2ALDH1A1KDM4ERAB9AMAPT
SCHEMBL271774 0.69 KDM4E (0.48) NQO2ALDH1A1KDM4ERAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762196-B1 Heat developable light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-10-27 EP disclosed
EP-0762196-A1 Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1997-03-12 EP disclosed