Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.63 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.62 |
| ▸ | PGK1 | P00558 | 2/20 | 0.61 |
| ▸ | PGK2 | P07205 | 2/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426439 | 1.00 | ADORA3 (0.63) | ADORA3SLC29A1PGK1PGK2ADORA2A | |
| SCHEMBL8422649 | 0.94 | ADORA3 (0.66) | ADORA3SLC29A1PGK1PGK2ADORA2A | |
| SCHEMBL8422643 | 0.94 | ADORA3 (0.66) | ADORA3SLC29A1PGK1PGK2ADORA2A | |
| SCHEMBL8426311 | 0.94 | ADORA3 (0.60) | ADORA3SLC29A1PGK1PGK2ADORA1 | |
| SCHEMBL8426308 | 0.94 | ADORA3 (0.60) | ADORA3SLC29A1PGK1PGK2ADORA1 | |
| SCHEMBL8423342 | 0.93 | ADORA3 (0.64) | ADORA3SLC29A1PGK1PGK2ADORA2A | |
| SCHEMBL8423332 | 0.93 | ADORA3 (0.64) | ADORA3SLC29A1PGK1PGK2ADORA2A | |
| SCHEMBL18660509 | 0.93 | ADORA3 (0.69) | ADORA3SLC29A1PGK1PGK2ADORA2A | |
| SCHEMBL8423228 | 0.92 | ADORA3 (0.59) | ADORA3SLC29A1PGK1PGK2ADORA2A | |
| SCHEMBL8426595 | 0.92 | ADORA3 (0.59) | ADORA3SLC29A1PGK1PGK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955447-A | ADMINISTERING AS ANTICOAGULANT; TREATING CARDIOVASCULAR DISORDERS | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |
| US-5721219-A | ANTICOAGULANTS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-02-24 | — | — | US | disclosed |
| EP-0683789-B1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | ASTRA PHARMA PROD (GB) | 1997-11-05 | — | — | EP | disclosed |