Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788407 | 0.78 | POLB (0.49) | BCHEMAPTALOX12HTTNPSR1 | |
| SCHEMBL30966337 | 0.78 | BCHE (1.00) | BCHEMAPTALOX12HTTNPSR1 | |
| SCHEMBL29272021 | 0.78 | BCHE (1.00) | BCHEMAPTALOX12HTTNPSR1 | |
| SCHEMBL4781585 | 0.73 | CYP3A4 (0.61) | BCHEMAPTALOX12HTTNPSR1 | |
| SCHEMBL15775420 | 0.72 | BCHE (0.71) | BCHEMAPTALOX12HTTNPSR1 | |
| SCHEMBL25305581 | 0.72 | BCHE (0.66) | BCHEMAPTALOX12HTTNPSR1 | |
| SCHEMBL29272023 | 0.72 | BCHE (0.74) | BCHEMAPTALOX12HTTNOX1 | |
| SCHEMBL30966336 | 0.72 | BCHE (0.74) | BCHEMAPTALOX12HTTNOX1 | |
| SCHEMBL12340051 | 0.71 | BCHE (0.56) | BCHEMAPTALOX12HTTNPSR1 | |
| SCHEMBL8739172 | 0.70 | BCHE (0.76) | BCHENOX1KMT2AMEN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861394-A | COMPOUNDS AS ANTIISCHEMIC AGENTS, TREATMENT OF STROKES, ANTIHEMORRHEGENIC AGENTS, ANTIDEPRESSANTS OR TREATMENT OF SICKKLE CELL ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | claimed |