Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 6/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426655 | 0.78 | BCHE (0.77) | BCHEMAPTMEN1KMT2AHTT | |
| SCHEMBL8788369 | 0.71 | BCHE (0.53) | BCHEMEN1KMT2ANOX1LMNA | |
| SCHEMBL7127793 | 0.67 | BCHE (0.49) | BCHEKMT2ANOX1LMNA | |
| SCHEMBL589501 | 0.66 | ALDH1A1 (0.65) | POLBTAAR1MAPTMEN1KMT2A | |
| SCHEMBL1616693 | 0.66 | MDM2 (0.61) | POLBBCHETAAR1MAPTMEN1 | |
| SCHEMBL13679756 | 0.66 | POLB (1.00) | POLBBCHETAAR1MAPTSMN1; SMN2 | |
| SCHEMBL2656818 | 0.65 | BCHE (0.63) | BCHENOX1LMNA | |
| SCHEMBL8809142 | 0.65 | HDAC6 (0.49) | POLBBCHEMEN1KMT2AHTT | |
| SCHEMBL1616690 | 0.65 | MDM2 (0.59) | POLBBCHETAAR1MEN1KMT2A | |
| SCHEMBL28109662 | 0.64 | MDM2 (0.44) | POLBBCHETAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777481-A1 | USE OF N-SUBSTITUTED PHENOTHIAZINES | BAYER AG (DE) | 1997-06-11 | — | — | EP | claimed |
| WO-1996005837-A1 | USE OF N-SUBSTITUTED PHENOTHIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-29 | — | — | WO | claimed |