SCHEMBL8427136

SCHEMBL8427136

CNc1ccc(O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.68
MEN1 O00255 7/20 0.68
KMT2A Q03164 7/20 0.68
MAOA P21397 4/20 0.68
MAPK1 P28482 6/20 0.61
TDP1 Q9NUW8 5/20 0.61
L3MBTL1 Q9Y468 4/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
RAB9A P51151 3/20 0.61
PABPC1 P11940 2/20 0.61
EGFR P00533 2/20 0.61
MCL1 Q07820 5/20 0.56
POLB P06746 4/20 0.56
HPGD P15428 3/20 0.56
BLM P54132 2/20 0.56
CSNK1A1 P48729 1/20 0.56
CSNK1D P48730 1/20 0.56
PLEC Q15149 1/20 0.56
CSNK1G1 Q9HCP0 1/20 0.56
LMNA P02545 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30341064 1.00 MAPT (0.68) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL29358770 0.89 MAPT (0.74) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL55230 0.89 MAPT (0.74) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL29419222 0.89 MAPT (0.74) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL29362988 0.87 CYP19A1 (0.53) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL18984691 0.87 CYP19A1 (0.53) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL1972769 0.87 CYP19A1 (0.53) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL16473098 0.87 CYP19A1 (0.53) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL13527359 0.83 MAPT (0.67) MAPTMEN1KMT2AMAOAMAPK1
SCHEMBL16140780 0.83 MEN1 (0.63) MAPTMEN1KMT2AMAOAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117050404-A Environment-friendly color-smoke-emitting tread rubber composition 东营瑞升橡胶有限公司 2023-11-14 CN claimed
CN-117050404-A Environment-friendly color-smoke-emitting tread rubber composition 东营瑞升橡胶有限公司 2023-11-14 CN disclosed
US-9630982-B2 Colored charged silsesquioxanes BASF SE (DE) 2017-04-25 US disclosed
US-9605114-B2 Polyphosphazenes THE SECRETARY OF STATE FOR DEFENCE (GB) 2017-03-28 US disclosed
US-9605114-B2 Polyphosphazenes THE SECRETARY OF STATE FOR DEFENCE (GB) 2017-03-28 US disclosed
US-9580450-B2 2017-02-28 US disclosed
US-9556314-B2 Polyphosphazenes THE SECRETARY OF STATE FOR DEFENCE (GB) 2017-01-31 US disclosed
US-9228063-B2 Colored charged silsesquioxanes BASF SE (DE) 2016-01-05 US disclosed
US-20150141540-A1 POLYPHOSPHAZENES THE SECRETARY OF STATE FOR DEFENCE (GB) 2015-05-21 US disclosed
WO-2014170833-A2 COLORED CHARGED SILSESQUIOXANES BASF SE (DE) 2014-10-23 WO disclosed
WO-2013150444-A1 COLORED CHARGED SILSESQUIOXANES BASF SE (DE) 2013-10-10 WO disclosed
US-20120141402-A1 NANOSCOPIC HAIR CARE PRODUCTS BOSTON COSMETICS, LLC 2012-06-07 US disclosed
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition SAKAMOTO JUN (JP) 2012-02-09 US disclosed
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition SAKAMOTO JUN (JP) 2012-02-09 US disclosed
US-7968084-B2 A Hair dye IN AN INTIMATE RELATIONSHIP TO A POLYMERIC NANOSTRUCTURE having hair-reactive functional groups to be covalently bound to or immobilized onto or in the hair BOSTON COSMETICS, LLC (US) 2011-06-28 US disclosed
US-20100209735-A1 Polyester resin compositions, polyester film, and magnetic recording medium YOSHIMURA HITOSHI 2010-08-19 US disclosed
US-20100209735-A1 Polyester resin compositions, polyester film, and magnetic recording medium YOSHIMURA HITOSHI 2010-08-19 US disclosed
US-7709594-B2 Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium TORAY INDUSTRIES, INC. (JP) 2010-05-04 US disclosed
US-7709594-B2 Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium TORAY INDUSTRIES, INC. (JP) 2010-05-04 US disclosed
US-5942292-A Spacer for liquid crystal display and liquid crystal display made by using the same KAO CORPORATION (JP) 1999-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition PUF60, RPS24, SRP54 MAPT 2627/4885MEN1 2460/4885KMT2A 1503/4885
US-20120141402-A1 NANOSCOPIC HAIR CARE PRODUCTS TYR, CUTA, SUCLG1 MAPT 767/4885MEN1 3038/4885KMT2A 340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.