SCHEMBL8427232

SCHEMBL8427232

Cc1ccccc1Oc1c(C)cc(O)cc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
NPC1 O15118 1/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TDP1 Q9NUW8 1/20 0.41
BACE1 P56817 1/20 0.41
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
MAPT P10636 2/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
MPI P34949 1/20 0.39
RECQL P46063 1/20 0.39
HSP90AA1 P07900 1/20 0.39
ATM Q13315 1/20 0.39
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374404 0.91 MEN1 (0.47) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL11202500 0.79 MEN1 (0.47) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL2864860 0.77 KMT2A (0.48) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL9742303 0.76 SMN1; SMN2 (0.47) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL8375486 0.76 MEN1 (0.47) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL11588960 0.75 MEN1 (0.50) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL2865455 0.74 MAOB (0.53) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL1836316 0.74 MEN1 (0.46) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL31093937 0.74 MEN1 (0.46) KMT2AMEN1NPC1TSHRRAB9A
SCHEMBL1834874 0.73 TSHR (0.44) KMT2AMEN1NPC1TSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11185297-A None JP disclosed
JP-H11185297-A OPTICAL RECORD MEDIUM YAMAMOTO CHEM INC 1999-07-09 JP disclosed