SCHEMBL10098714

SCHEMBL10098714

Cc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.76

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.76
▸ L3MBTL1 Q9Y468 1/20 0.76
▸ MEN1 O00255 2/20 0.64
▸ POLB P06746 2/20 0.64
▸ KMT2A Q03164 2/20 0.64
▸ ALPL P05186 1/20 0.64
▸ ALPI P09923 1/20 0.64
▸ ALPG P10696 1/20 0.64
▸ ATM Q13315 1/20 0.62
▸ PLEC Q15149 1/20 0.62
▸ CA9 Q16790 15/20 0.58
▸ CA1 P00915 13/20 0.58
▸ CA2 P00918 13/20 0.58
▸ DNASE1L3 Q13609 1/20 0.56
▸ PRMT1 Q99873 1/20 0.56
▸ CA12 O43570 5/20 0.56
▸ CA14 Q9ULX7 2/20 0.53
▸ CA7 P43166 2/20 0.51
▸ ESR1 P03372 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12045940 0.92 USP2 (0.68) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL12900563 0.89 USP2 (0.72) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL12231697 0.87 CA9 (0.75) USP2L3MBTL1CA9CA1CA2
SCHEMBL1437042 0.87 USP2 (0.78) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20254033 0.87 USP2 (0.77) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14646715 0.87 USP2 (0.61) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL173061 0.87 USP2 (0.73) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL3481432 0.86 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL30023431 0.86 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL18239274 0.86 USP2 (0.76) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3294811-B1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY GROUP CORP (JP) 2024-02-28 — — EP disclosed
EP-3455299-B1 COMPOSITIONS COMPRISING A POLYMERIC DYE AND A CYCLODEXTRIN AND USES THEREOF SONY GROUP CORP (JP) 2024-01-17 — — EP disclosed
WO-2023242661-A2 POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-12-21 — — WO disclosed
EP-4137818-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS Sony Group Corporation (JP) 2023-02-22 — — EP disclosed
EP-3222617-B1 PSMA-TARGETING COMPOUNDS AND USES THEREOF UNIV JOHNS HOPKINS (US) 2022-07-06 — — EP disclosed
US-20210109104-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS Sony Group Corporation (JP) 2021-04-15 — — US disclosed
WO-2021067483-A1 NUCLEOTIDE PROBES SONY CORPORATION (JP) 2021-04-08 — — WO disclosed
US-10626438-B2 Fluorescent substrates for determining lysine modifying enzyme activity THE BROAD INSTITUTE, INC. (US) 2020-04-21 — — US disclosed
WO-2019182765-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS SONY CORPORATION (JP) 2019-09-26 — — WO disclosed
US-20180155760-A1 FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY BROAD INST INC (US) 2018-06-07 — — US disclosed
US-20110229980-A1 OLIGONUCLEOTIDE PROBE AND USE THEREOF NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2011-09-22 — — US disclosed
US-20110105496-A1 Methods For The Treatment Of Myosin Heavy Chain-Mediated Conditions Using 4,7-Dihydrothieno[2,3-B]Pyridine Compounds GILEAD COLORADO, INC. 2011-05-05 — — US disclosed
WO-2011018611-A1 REVERSIBLE COVALENT LINKAGE OF FUNCTIONAL MOLECULES UCL BUSINESS PLC (GB) 2011-02-17 — — WO disclosed
WO-2010097604-A2 NEW COMPOUNDS UCL BUSINESS PLC (GB) 2010-09-02 — — WO disclosed
WO-2009132310-A1 INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE THWART MYCOBACTERIAL GROWTH WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-10-29 — — WO disclosed
US-7527928-B2 Reactions on a solid surface THIRD WAVE TECHNOLOGIES, INC. (US) 2009-05-05 — — US disclosed
WO-2009027679-A1 PROCESS FOR THE PREPARATION OF GUANIDINO SUBSTITUTED BI-AND POLYPHENYLS THAT ARE SUITABLE AS SMALL MOLECULE CARRIERS UCL BUSINESS PLC (GB) 2009-03-05 — — WO disclosed
US-20080221305-A1 Polynucleotides encoding novel adiponectin receptor variants BRISTOL-MYERS SQUIBB COMPANY 2008-09-11 — — US disclosed
US-7312086-B2 Methods of diagnosing colon adenocarcinoma using the human g-protein coupled receptor hgprbmy23 BRISTOL-MYERS SQUIBB COMPANY (US) 2007-12-25 — — US disclosed
EP-1084269-B1 NOVEL PEROXIDASE SUBSTRATES AND THEIR USE IN CATALYZED REPORTER DEPOSITION PERKINELMER LAS INC (US) 2007-04-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221305-A1 Polynucleotides encoding novel adiponectin receptor variants ADIPOR1, ADIPOR2, FABP4 USP2 4016/4885L3MBTL1 3518/4885MEN1 3728/4885
US-20180155760-A1 FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY KDM1A, MAN2B1, KDM3A USP2 619/4885L3MBTL1 242/4885MEN1 536/4885
US-20110229980-A1 OLIGONUCLEOTIDE PROBE AND USE THEREOF DCLRE1B, NSUN2, MTX2 USP2 2107/4885L3MBTL1 28/4885MEN1 2002/4885
US-10626438-B2 Fluorescent substrates for determining lysine modifying enzyme activity KDM1A, MAN2B1, KDM3A USP2 619/4885L3MBTL1 242/4885MEN1 536/4885
US-20110105496-A1 Methods For The Treatment Of Myosin Heavy Chain-Mediated Conditions Using 4,7-Dihydrothieno[2,3-B]Pyridine Compounds MYH2, MYLK2, TNNI3 USP2 2470/4885L3MBTL1 2800/4885MEN1 3190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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