Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13161133 | 1.00 | REN (0.43) | RENAXLMERTKGRM5 | |
| SCHEMBL3272255 | 1.00 | REN (0.43) | RENAXLMERTKGRM5 | |
| SCHEMBL3267971 | 0.94 | REN (0.42) | RENAXLMERTK | |
| SCHEMBL4583046 | 0.94 | REN (0.42) | RENAXLMERTK | |
| SCHEMBL3267808 | 0.93 | REN (0.42) | RENGRM5 | |
| SCHEMBL13161111 | 0.93 | REN (0.42) | RENGRM5 | |
| SCHEMBL13161108 | 0.93 | REN (0.48) | RENAXLMERTKGRM5 | |
| SCHEMBL3272419 | 0.93 | REN (0.48) | RENAXLMERTKGRM5 | |
| SCHEMBL8428938 | 0.93 | REN (0.48) | RENAXLMERTKGRM5 | |
| SCHEMBL13161112 | 0.93 | REN (0.42) | RENAXLMERTKGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987834-A2 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2008-11-05 | — | — | EP | disclosed |