Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424148 | 0.88 | APP (0.58) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL6945778 | 0.84 | MAPT (0.56) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8020214 | 0.83 | KMT2A (0.66) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8423947 | 0.82 | KMT2A (0.60) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL4661824 | 0.81 | MAPT (0.61) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL11870457 | 0.78 | MEN1 (0.67) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL4663160 | 0.77 | MAPT (0.62) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL13122202 | 0.77 | NPC1 (0.59) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8428074 | 0.77 | GAA (0.59) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8427533 | 0.77 | MAPT (0.65) | ALDH1A1MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |