SCHEMBL8427972

SCHEMBL8427972

CC[Si](CC)(CC)O[C@H](C)[C@H](CN)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
GABRR1 P24046 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27812618 0.75 SLC1A3 (0.32) SLC1A3SLC1A2SLC1A1GABRR1
SCHEMBL8428511 0.75 SLC1A3 (0.32) SLC1A3SLC1A2SLC1A1GABRR1
SCHEMBL8430109 0.71 SLC1A3 (0.36) SLC1A3SLC1A2SLC1A1
SCHEMBL16967373 0.68
SCHEMBL636884 0.68
SCHEMBL4738598 0.68
SCHEMBL4738608 0.67 ACE (0.42) SLC1A3SLC1A2SLC1A1GABRR1
SCHEMBL4990636 0.67 ACE (0.42) SLC1A3SLC1A2SLC1A1GABRR1
SCHEMBL22636075 0.67 ACE (0.42) SLC1A3SLC1A2SLC1A1GABRR1
Hydrochloric Acid SCHEMBL6235278 0.66 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0742223-B1 A method of preparing a derivative of optically active azetidin-2-one TAKASAGO PERFUMERY CO LTD (JP) 1999-11-17 EP disclosed
US-5712388-A Method of preparing a derivative of optically active azetidin-2-one TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-01-27 US disclosed
EP-0742223-A1 A method of preparing a derivative of optically active azetidin-2-one Takasago International Corporation (JP) 1996-11-13 EP disclosed