Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 2/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633102 | 0.87 | KMT2A (0.48) | MEN1KMT2ATSHR | |
| SCHEMBL8633106 | 0.82 | SLC1A3 (0.37) | SLC1A3SLC1A2SLC1A1GABBR2GABBR1 | |
| SCHEMBL8633109 | 0.82 | TAAR1 (0.37) | TAAR1MEN1KMT2AAPAF1NR4A2 | |
| SCHEMBL8427972 | 0.71 | SLC1A3 (0.33) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23699060 | 0.69 | MME (0.51) | TAAR1GABBR2GABBR1 | |
| SCHEMBL4984168 | 0.69 | MME (0.51) | TAAR1GABBR2GABBR1 | |
| SCHEMBL8428511 | 0.69 | SLC1A3 (0.32) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL708488 | 0.67 | ALDH1A1 (0.35) | TAAR1TSHR | |
| SCHEMBL20875949 | 0.67 | CYP2D6 (0.61) | SLC1A3SLC1A2SLC1A1TAAR1GABBR2 | |
| SCHEMBL4986173 | 0.67 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1TAAR1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742223-B1 | A method of preparing a derivative of optically active azetidin-2-one | TAKASAGO PERFUMERY CO LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| EP-0742223-A1 | A method of preparing a derivative of optically active azetidin-2-one | Takasago International Corporation (JP) | 1996-11-13 | — | — | EP | disclosed |