Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.40 |
| ▸ | MEN1 | O00255 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428139 | 1.00 | KMT2A (0.40) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL6951671 | 0.95 | KMT2A (0.43) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL6951666 | 0.95 | KMT2A (0.43) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8425736 | 0.89 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8425734 | 0.89 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8425498 | 0.89 | MEN1 (0.39) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8425496 | 0.89 | MEN1 (0.39) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8428125 | 0.88 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8428127 | 0.88 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8425576 | 0.87 | KAT8 (0.41) | KMT2AMEN1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |