Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148382 | 0.90 | PTK2 (0.45) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8428238 | 0.83 | NPC1 (0.42) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8799205 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4ETSHRMAPK1 | |
| SCHEMBL8132723 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8141408 | 0.80 | MAPT (0.39) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8133787 | 0.80 | CHEK1 (0.44) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL8142631 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8149324 | 0.78 | PTK2 (0.41) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8142644 | 0.78 | HSD17B10 (0.37) | ALDH1A1MAPTKDM4ELMNAHPGD | |
| SCHEMBL8148216 | 0.78 | LPAR1 (0.41) | ALDH1A1MAPTKDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880147-A | Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use | SANKYO COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |