Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | GIGYF2 | Q6Y7W6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5075016 | 0.82 | TDP1 (0.47) | TDP1CNR1CNR2CA12CA1 | |
| SCHEMBL6033324 | 0.77 | TDP1 (0.55) | TDP1CNR1CNR2CA12CA1 | |
| SCHEMBL179912 | 0.77 | TDP1 (0.55) | TDP1CNR1CNR2CA12CA1 | |
| SCHEMBL14417100 | 0.77 | TDP1 (0.55) | TDP1CNR1CNR2CA12CA1 | |
| SCHEMBL18780618 | 0.77 | TDP1 (0.55) | TDP1CNR1CNR2CA12CA1 | |
| SCHEMBL4455260 | 0.77 | TDP1 (0.55) | TDP1CNR1CNR2CA12CA1 | |
| SCHEMBL12569327 | 0.77 | TDP1 (0.55) | TDP1CNR1CNR2CA12CA1 | |
| SCHEMBL3622089 | 0.76 | TDP1 (0.54) | TDP1CNR1CNR2CA12CA1 | |
| SCHEMBL2373483 | 0.76 | TDP1 (0.52) | TDP1CNR1CA12CA1CA2 | |
| SCHEMBL4153459 | 0.75 | TDP1 (0.48) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955290-A | CONTACTING CELL WHICH COEXPRESSES RECEPTOR AND KINASE WITH TEST AGONIST, DETERMINING AMOUNT OF TYROSINE PHOSPHORYLATION | REGENERON PHARMACEUTICALS, INC. (US) | 1999-09-21 | — | — | US | disclosed |