Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 8/20 | 0.45 |
| ▸ | CA1 | P00915 | 8/20 | 0.45 |
| ▸ | CA2 | P00918 | 8/20 | 0.45 |
| ▸ | CA9 | Q16790 | 8/20 | 0.45 |
| ▸ | HLCS | P50747 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428342 | 0.82 | TDP1 (0.49) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL4153459 | 0.80 | TDP1 (0.48) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL4522069 | 0.78 | TDP1 (0.52) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL244669 | 0.77 | TDP1 (0.49) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL1639628 | 0.75 | TDP1 (0.49) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL17114632 | 0.75 | TDP1 (0.70) | TDP1CA12CA1CA2CA9 | |
| Biotin SCHEMBL2192463 | 0.74 | TDP1 (0.60) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL5789780 | 0.74 | TDP1 (0.51) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL4566720 | 0.74 | HLCS (0.45) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL29613855 | 0.73 | TDP1 (0.57) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940444-A2 | METHODS OF PREPARING TARGETED IMMUNOLIPOSOMES | Centocor, Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007048121-A2 | METHODS OF PREPARING TARGETED IMMUNOLIPOSOMES | CENTOCOR, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| EP-0990142-A4 | MULTIPLEXED MOLECULAR ANALYSIS APPARATUS AND METHOD | GENOMETRIX GENOMICS INC (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-0990142-A1 | MULTIPLEXED MOLECULAR ANALYSIS APPARATUS AND METHOD | Genometrix Incorporated (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0914471-A2 | METHOD FOR DISSOCIATING BIOTIN COMPLEXES | SEQUENOM, INC. (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998029736-A1 | MULTIPLEXED MOLECULAR ANALYSIS APPARATUS AND METHOD | GENOMETRIX INCORPORATED (US) | 1998-07-09 | — | — | WO | disclosed |
| WO-1997043617-A2 | METHOD FOR DISSOCIATING BIOTIN COMPLEXES | SEQUENOM, INC. (US) | 1997-11-20 | — | — | WO | disclosed |