Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 6/20 | 0.38 |
| ▸ | TGM6 | O95932 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PROC | P04070 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423761 | 0.92 | F10 (0.38) | MMP2MMP9F10F2TGM2 | |
| SCHEMBL8425687 | 0.88 | MGAT2 (0.35) | MMP2MMP9F10F2TGM2 | |
| SCHEMBL8423970 | 0.84 | F10 (0.43) | MMP2MMP9F10F2TGM2 | |
| SCHEMBL8425839 | 0.84 | F10 (0.55) | F10F2PLGPROC | |
| SCHEMBL8425646 | 0.84 | F10 (0.41) | MMP2MMP9F10F2TGM2 | |
| SCHEMBL2329425 | 0.83 | F10 (0.52) | MMP2MMP9F10F2PLG | |
| SCHEMBL2325807 | 0.82 | F10 (0.50) | MMP2MMP9F10F2TGM2 | |
| SCHEMBL2325817 | 0.82 | F10 (0.50) | MMP2MMP9F10F2TGM2 | |
| SCHEMBL8428420 | 0.81 | F10 (0.33) | MMP2MMP9F10F2HPN | |
| SCHEMBL2333896 | 0.81 | F10 (0.52) | MMP2MMP9F10F2TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |