Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.43 |
| ▸ | F2 | P00734 | 7/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 5/20 | 0.39 |
| ▸ | TGM6 | O95932 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PROC | P04070 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425646 | 0.92 | F10 (0.41) | F10F2MMP2MMP9TGM2 | |
| SCHEMBL2329425 | 0.86 | F10 (0.52) | F10F2MMP2MMP9PLG | |
| SCHEMBL2325807 | 0.84 | F10 (0.50) | F10F2MMP2MMP9TGM2 | |
| SCHEMBL2325817 | 0.84 | F10 (0.50) | F10F2MMP2MMP9TGM2 | |
| SCHEMBL8428362 | 0.84 | MMP2 (0.39) | F10F2MMP2MMP9TGM2 | |
| SCHEMBL8424709 | 0.84 | F10 (0.42) | F10F2MMP2MMP9TGM2 | |
| SCHEMBL2333896 | 0.82 | F10 (0.52) | F10F2MMP2MMP9TGM2 | |
| SCHEMBL8423761 | 0.82 | F10 (0.38) | F10F2MMP2MMP9TGM2 | |
| SCHEMBL8425627 | 0.82 | F10 (0.61) | F10F2PLGPROCPRSS1 | |
| SCHEMBL2327401 | 0.81 | F10 (0.45) | F10F2MMP2MMP9PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |