Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | DTYMK | P23919 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640851 | 1.00 | FGFR1 (0.44) | FGFR1FGFR4POLBKDM4EELANE | |
| SCHEMBL14262719 | 0.79 | FGFR1 (0.50) | FGFR1FGFR4POLBKDM4EELANE | |
| SCHEMBL15157126 | 0.78 | KDM4E (0.44) | FGFR1FGFR4POLBKDM4EPARP1 | |
| SCHEMBL30677230 | 0.78 | ELANE (0.41) | POLBKDM4EELANEGPR119MAPT | |
| SCHEMBL2363023 | 0.78 | ELANE (0.49) | POLBKDM4EELANEEGFRITK | |
| SCHEMBL29754118 | 0.78 | ELANE (0.49) | POLBKDM4EELANEEGFRITK | |
| SCHEMBL21431482 | 0.77 | CYP11B2 (0.44) | POLBKDM4EELANECKS1BSKP1 | |
| SCHEMBL31690642 | 0.77 | CYP11B2 (0.44) | POLBKDM4EELANECKS1BSKP1 | |
| SCHEMBL30308887 | 0.77 | POLB (0.42) | POLBKDM4EELANEGPR119MAPT | |
| SCHEMBL31037735 | 0.77 | KDM4E (0.53) | FGFR1FGFR4KDM4EELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117616021-A | (R) -glutarimide CRBN ligands and methods of use | 百济神州有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-112724134-B | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2022-04-01 | — | — | CN | disclosed |
| US-5859007-A | TREATMENT OF DIABETES, OBESITY | GLAXO WELLCOME INC. (US) | 1999-01-12 | — | — | US | disclosed |