Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251684 | 0.96 | LMNA (0.61) | LMNAALDH1A1TSHRTHRBRECQL | |
| SCHEMBL5915010 | 0.92 | LMNA (0.57) | LMNAALDH1A1TSHRTHRBRECQL | |
| Hydrochloric Acid SCHEMBL10478237 | 0.92 | LMNA (0.57) | LMNAALDH1A1TSHRTHRBRECQL | |
| SCHEMBL27692789 | 0.82 | LMNA (0.47) | LMNAALDH1A1TSHRTHRBRECQL | |
| SCHEMBL7592949 | 0.80 | LMNA (0.53) | LMNAALDH1A1TSHRTHRBRECQL | |
| SCHEMBL1706438 | 0.80 | — | — | |
| Dichloroacetic Acid SCHEMBL2421911 | 0.78 | — | — | |
| SCHEMBL6569420 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL8555530 | 0.77 | — | — | |
| SCHEMBL28196148 | 0.77 | LMNA (0.42) | LMNAALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36234-E | Aspartic acid copolymers and their preparation | DONLAR CORPORATION (US) | 1999-06-22 | — | — | US | claimed |
| US-RE36234-E | Aspartic acid copolymers and their preparation | DONLAR CORPORATION (US) | 1999-06-22 | — | — | US | disclosed |
| US-5478919-A | Condensation polymerization of aspartic acid precursors and amino, hydroxy or carboxy-functional monomers to form polysuccinimide copolymer; hydrolysis to aspartic acid copolymer | DONLAR CORPORATION (US) | 1995-12-26 | — | — | US | disclosed |