Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 14/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776664 | 0.73 | BCHE (1.00) | BCHEACHEMAPTNOX1TSHR | |
| SCHEMBL4779900 | 0.72 | BCHE (0.70) | BCHEACHEMAPTNOX1GFER | |
| Hydrochloric Acid SCHEMBL5804919 | 0.71 | BCHE (0.68) | BCHEACHEMAPTNOX1GFER | |
| SCHEMBL28460389 | 0.70 | BCHE (0.62) | BCHEACHENOX1POLBATM | |
| SCHEMBL8136843 | 0.68 | GAA (0.39) | BCHEACHEGAAMAPTNOX1 | |
| SCHEMBL8965779 | 0.68 | MAOA (0.41) | BCHEACHEGAAMAPTNOX1 | |
| Hydrochloric Acid SCHEMBL27595175 | 0.67 | NOX1 (0.57) | BCHEACHEGAAMAPTNOX1 | |
| SCHEMBL341905 | 0.67 | NOX1 (1.00) | BCHEACHEGAAMAPTNOX1 | |
| SCHEMBL30198410 | 0.67 | NOX1 (1.00) | BCHEACHEGAAMAPTNOX1 | |
| SCHEMBL17999646 | 0.67 | BCHE (0.46) | BCHEACHEGAAMAPTNOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861394-A | COMPOUNDS AS ANTIISCHEMIC AGENTS, TREATMENT OF STROKES, ANTIHEMORRHEGENIC AGENTS, ANTIDEPRESSANTS OR TREATMENT OF SICKKLE CELL ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |