Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159964 | 0.90 | ALDH1A1 (0.55) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7038851 | 0.86 | HPGD (0.42) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7033484 | 0.81 | MEN1 (0.43) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7033483 | 0.81 | MEN1 (0.43) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7157387 | 0.78 | ALDH1A1 (0.54) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7205001 | 0.77 | ALDH1A1 (0.54) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL21954535 | 0.75 | ALDH1A1 (0.53) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL21418918 | 0.75 | ALDH1A1 (0.60) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL16576319 | 0.75 | ALDH1A1 (0.60) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL20557340 | 0.75 | ALDH1A1 (0.60) | HPGDALDH1A1CHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880294-A | D-pentofuranose derivatives and process for preparing the same | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0842942-A1 | D-PENTOFURANOSE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |