Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425942 | 0.93 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL30646054 | 0.92 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16405348 | 0.88 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8014847 | 0.86 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL25328275 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDLPAR1 | |
| SCHEMBL30121599 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDLPAR1 | |
| SCHEMBL30258755 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDLPAR1 | |
| SCHEMBL30259226 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDLPAR1 | |
| SCHEMBL7925576 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDLPAR1 | |
| SCHEMBL30757948 | 0.84 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956318-A1 | RADIATION-CURABLE COMPOSITION | DSM N.V. (NL) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998033855-A1 | RADIATION-CURABLE COMPOSITION | DSM N.V. (NL) | 1998-08-06 | — | — | WO | disclosed |