Ethylene Glycol

Ethylene Glycol

SCHEMBL8429233

C(OCC1CO1)C1CO1.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.C=CC.OCCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
TSHR P16473 4/20 0.45
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 3/20 0.32
CYP3A4 P08684 1/20 0.32
GLA P06280 1/20 0.32
MAPT P10636 2/20 0.30
HPGD P15428 2/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
PPARG P37231 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL475460 1.00 ALDH1A1 (0.55) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Ethylene Glycol SCHEMBL1095963 1.00 ALDH1A1 (0.55) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Ethylene Glycol SCHEMBL5922943 1.00 ALDH1A1 (0.55) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Ethylene Glycol SCHEMBL1094764 1.00 ALDH1A1 (0.55) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Propene SCHEMBL2778270 0.91 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Propene SCHEMBL2776876 0.91 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Propene SCHEMBL26630 0.91 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Propene SCHEMBL2777932 0.91 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Acrylic Acid SCHEMBL8642804 0.89 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
Butadiene SCHEMBL3302346 0.89 ALDH1A1 (0.57) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672950-B1 WATERLESS LITHOGRAPHIC PLATE TORAY INDUSTRIES (JP) 1999-11-24 EP disclosed