Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CETP | P11597 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19819925 | 0.88 | SPHK1 (0.52) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL2384900 | 0.88 | GPR84 (0.55) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL136612 | 0.87 | SPHK1 (0.62) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL10607850 | 0.87 | SPHK1 (0.62) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL13825654 | 0.87 | SPHK1 (0.62) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL3344513 | 0.87 | SPHK1 (0.62) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL7756046 | 0.87 | SPHK1 (0.62) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL10605211 | 0.87 | SPHK1 (0.62) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL2385582 | 0.87 | SPHK1 (0.62) | GPR84SPHK1FFAR1CYP2D6MAPT | |
| SCHEMBL27963355 | 0.87 | SPHK1 (0.62) | GPR84SPHK1FFAR1CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104878044-A | Lipid compound siRNA (small interfering ribonucleic acid) transfection reagent | CHANGZHOU BIO TRAN BIO TECHNOLOGY LTD | 2015-09-02 | — | — | CN | disclosed |
| CN-102985548-A | Compositions comprising cationic amphiphiles and co-lipids for delivery of therapeutic molecules | CUI KUNYUAN | 2013-03-20 | — | — | CN | disclosed |
| CN-102727436-A | Nucleic acid liposome drug preparation | BIOMICS BIOTECHNOLOGIES CO LTD | 2012-10-17 | — | — | CN | disclosed |
| EP-0954339-A2 | CATIONIC AMPHIPHILE COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | Genzyme Corporation (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0954338-A2 | CATIONIC AMPHIPHILE/DNA COMPLEXES | Genzyme Corporation (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998002190-A2 | CATIONIC AMPHIPHILE/DNA COMPLEXES | GENZYME CORPORATION (US) | 1998-01-22 | — | — | WO | disclosed |
| WO-1998002191-A2 | CATIONIC AMPHIPHILE COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1998-01-22 | — | — | WO | disclosed |