Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 15/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431088 | 0.93 | HPGD (0.43) | PPARGCYP1A2 | |
| SCHEMBL4575066 | 0.88 | CYP1B1 (0.46) | XDHPPARGQPCTEGFRRET | |
| SCHEMBL4574734 | 0.88 | CYP1B1 (0.46) | XDHPPARGQPCTEGFRRET | |
| SCHEMBL4575775 | 0.88 | CYP1B1 (0.46) | XDHPPARGQPCTEGFRRET | |
| SCHEMBL8306985 | 0.85 | BRD4 (0.47) | QPCT | |
| SCHEMBL4575214 | 0.84 | KDM1A (0.49) | XDHKDM1ACYP1A2 | |
| SCHEMBL8576791 | 0.83 | QPCT (0.42) | PPARGQPCTEGFRRETKDR | |
| SCHEMBL8427180 | 0.83 | XDH (0.55) | XDHPPARGEGFRRETKDR | |
| SCHEMBL8431111 | 0.83 | CYP1B1 (0.57) | XDHPPARGEGFRRETKDR | |
| SCHEMBL8309780 | 0.82 | BRD4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |