Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431119 | 0.78 | KDM4E (0.41) | KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15108831 | 0.76 | KDM4E (0.47) | KDM4EKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL20033212 | 0.72 | KMT2A (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL23812865 | 0.71 | ALDH1A1 (0.40) | KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2278969 | 0.70 | ALDH1A1 (0.52) | KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5435743 | 0.69 | HTT (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28020083 | 0.69 | CYP3A4 (0.45) | KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13596324 | 0.69 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2LMNACA1 | |
| SCHEMBL10052627 | 0.69 | KMT2A (0.33) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8429387 | 0.68 | MEN1 (0.35) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945382-A | AND A METHOD OF THEIR PREPARATION BY CHLORINATION OF AN INTERMEDIATE ARYLPYRAZOLE; PROTECTION AGAINST FUNGAL DISEASES IN TOMATO, RICE, AND WHEAT PLANTS | RHONE-POULENC AGROCHIMIE (FR) | 1999-08-31 | — | — | US | disclosed |