Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL600183 | 0.87 | — | — | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28542642 | 0.84 | TSHR (0.38) | ALDH1A1HSD17B10PPARDMEN1KMT2A | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL1502086 | 0.84 | PPARD (0.39) | ALDH1A1HSD17B10PPARDMEN1KMT2A | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL8429419 | 0.84 | PPARD (0.39) | ALDH1A1HSD17B10PPARDMEN1KMT2A | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL4585075 | 0.84 | PPARD (0.39) | ALDH1A1HSD17B10PPARDMEN1KMT2A | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28537563 | 0.82 | TSHR (0.36) | ALDH1A1HSD17B10PPARDMEN1KMT2A | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28537561 | 0.82 | TSHR (0.36) | ALDH1A1HSD17B10PPARDMEN1KMT2A | |
| O,O-Diethyl S-Hydrogen Phosphorothioate SCHEMBL28187474 | 0.79 | POLB (0.36) | ALDH1A1HSD17B10PPARDLPAR2LPAR3 | |
| SCHEMBL1091581 | 0.78 | ALDH1A1 (0.36) | CYP2C9ALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL31031165 | 0.78 | ALDH1A1 (0.36) | CYP2C9ALDH1A1HSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155025-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050431-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2000-08-31 | — | — | WO | disclosed |