Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.52 |
| ▸ | HTR1D | P28221 | 17/20 | 0.51 |
| ▸ | HTR1B | P28222 | 14/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481656 | 0.87 | HTR1D (0.57) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7480624 | 0.86 | HTR1D (0.46) | CCR2HTR1DHTR1B | |
| SCHEMBL7480617 | 0.86 | CCR2 (0.61) | CCR2HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7484437 | 0.83 | HTR1D (0.55) | CCR2HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL8383630 | 0.82 | SLC6A4 (0.43) | HTR1DHTR1B | |
| SCHEMBL7483472 | 0.82 | HTR1D (0.66) | CCR2HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7489650 | 0.81 | HTR1D (0.60) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7480051 | 0.80 | HTR1D (0.52) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7481803 | 0.80 | HTR1D (0.74) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL7477707 | 0.80 | HTR1D (0.64) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962474-A | ANALGESICS; HEADACHES | ELI LILLY AND COMPANY (US) | 1999-10-05 | — | — | US | disclosed |