SCHEMBL8429557

SCHEMBL8429557

C[Si](C)(C)C[SiH2]c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8426694 0.79 ESR1 (0.34)
SCHEMBL29403408 0.76
SCHEMBL29400814 0.73
SCHEMBL311787 0.70
SCHEMBL8217604 0.70
SCHEMBL3682860 0.67 TP53 (0.38) PSIP1TP53
SCHEMBL10523373 0.67 TP53 (0.32) TP53
SCHEMBL23701274 0.65
SCHEMBL9510289 0.65
SCHEMBL448266 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714952-B1 Method of curing a siloxane polymer DOW CORNING ASIA LTD (JP) 1999-10-27 EP disclosed
US-5861468-A Curable siloxane polymer composition and method of curing DOW CORNING ASIA, LTD. (JP) 1999-01-19 US disclosed
EP-0714952-A1 Curable siloxane polymer composition and method of curing DOW CORNING ASIA, Ltd. (JP) 1996-06-05 EP disclosed