SCHEMBL8430002

SCHEMBL8430002

CCCCCCOCCOC(N)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.55
MAPT P10636 2/20 0.55
MEN1 O00255 1/20 0.55
THRB P10828 1/20 0.55
KMT2A Q03164 1/20 0.55
CES2 O00748 2/20 0.52
NAAA Q02083 1/20 0.48
DGKA P23743 1/20 0.48
EPHX1 P07099 1/20 0.46
TSHR P16473 2/20 0.44
HTR2C P28335 1/20 0.43
ALOX15 P16050 1/20 0.43
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
RAD52 P43351 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18683464 1.00 HTT (0.55) HTTMAPTMEN1THRBKMT2A
SCHEMBL11805300 0.98 HTT (0.52) HTTMAPTMEN1THRBKMT2A
SCHEMBL18683466 0.92 NAAA (0.53) HTTMAPTMEN1THRBKMT2A
SCHEMBL29139892 0.92 NAAA (0.53) HTTMAPTMEN1THRBKMT2A
SCHEMBL18683561 0.92 NAAA (0.53) HTTMAPTMEN1THRBKMT2A
SCHEMBL11554689 0.92 TSHR (0.48) HTTMAPTMEN1THRBKMT2A
SCHEMBL8431991 0.92 TSHR (0.48) HTTMAPTMEN1THRBKMT2A
SCHEMBL9004278 0.92 TSHR (0.48) HTTMAPTMEN1THRBKMT2A
SCHEMBL16763467 0.90 TSHR (0.46) HTTMAPTMEN1THRBKMT2A
SCHEMBL28897178 0.88 TSHR (0.52) HTTMAPTMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5892100-A DEHYDROHALOGENATION BY REACTION OF UNSATURATED ACID HALIDES WITH CARBAMATE IN THE PRESENCE OF HINDERED AMINE NIPPON PAINT CO., LTD. (JP) 1999-04-06 US disclosed
EP-0827953-A2 Method for producing N-acyl carbamate Nippon Paint Co., Ltd. (JP) 1998-03-11 EP disclosed
US-5583161-A COMPOSITION OBTAINED BY ADDING MONOALCOHOL TO POLYMER CROSSLINKED THROUGH ACYLCARBAMATE BOND AND HEATING NIPPON PAINT CO., LTD. (JP) 1996-12-10 US disclosed
EP-0730585-A1 ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1996-09-11 EP disclosed
US-5545696-A FILM FORMERS IN COATINGS PPG INDUSTRIES, INC. (US) 1996-08-13 US disclosed
US-5536835-A Etherified alkyl or arylcarbamylmethylated aminotriazines and curable compositions containing the same PPG INDUSTRIES, INC. (US) 1996-07-16 US disclosed
EP-0680994-A1 Re-Crosslinkable composition and method for recycling using the same Nippon Paint Co., Ltd. (JP) 1995-11-08 EP disclosed
WO-1995014677-A1 ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1995-06-01 WO disclosed
US-3990847-A Creaseproofing composition UNITED MERCHANTS AND MANUFACTURERS, INC. (US) 1976-11-09 US disclosed